REGENERATIVE ENDODONTICS-SYSTEMATIC REVIEW

Abstract

Regenerative endodontic materials represent a groundbreaking frontier in the field of dentistry revolutionizing the way we approach the restoration of damaged tooth tissue. This innovative approach seeks not only to repair but also to regenerate dental pulp a feat that was once considered elusive. This transformative approach heralds a new era in dentistry where the goal is not just to fix teeth but to regenerate them preserving oral health and function in the most biologically harmonious manner. Following PRISMA principles and the eligibility criteria each reviewer independently screened the titles and abstracts of the retrieved publications. Between the two reviewers disagreements or discrepancies were settled by consensus. A flowchart detailing the methodology used in the systematic review according to the standards provided by the Preferred Reporting Items for Systematic Reviews and Meta Analyses PRISMA was prepared. This systematic review concluded that endodontic regenerative therapy showed better results in certain parameters such as increase in root wall lengthening and thickening acute chronic periapical lesion healing and improved apical closure formation in the management of immature necrotic permanent teeth. This regenerative endodontic procedure REP proposes the use of a combination of antimicrobials and irrigants no canal wall instrumentation induced apical bleeding to form a blood clot and a tight seal into the root canal to promote healing. More clinical trials with a standardized protocol and defined clinical radiographic and histopathological outcomes with longer follow up periods are warranted.