SYNTHESIS, CHARACTERIZATION, AND EXPLORATION OF BIOLOGICAL ACTIVITIES OF 1,4(1,1’‑2 AMINOARYL BISDITHIAZOLIDINE‑3,3’ARYL) BENZENE

Abstract

Dithiazolidines are special and unique kind of five membered heterocyclic which has a unique structure containing two nitrogen and two sulphur atoms in it. It significantly benefits them since they can react to a wide range of substituents and thus offer much capacity to modulate functional behavior and chemical reactivity. The special structures as well as variety of applications of these compounds have drawn the attention of the various academic disciplines. The dithiazolidines are an effective intermediate in the chemical synthesis and facilitate the construction of complex molecular structures. Various dithiazolidine analogs have been found to possess great interest in the field of medicinal chemistry where they have demonstrated promising antibacterial activities, bioactive potential, and unique mechanisms of action. Moreover, they are also deemed to be appropriate to material science progress, namely, in the development of electronic materials, sensors, and functional polymers owing to their donor-acceptor properties and redox-activity. Dithiazolidines are also under investigation and the paper justifies their value in attaining fundamental science and at the same time, effective technologies. In this work, there was the production of 1, 4 -bis (R-aminothiocarbonyl) amino) benzene, which were used to determine their structures. At the time of antimicrobial performance measurement of the compounds it was observed that it had moderate or significant effect on a limited number of bacterial strains. This evidently denotes that a dithiazolidine frameworks is being considered in the era of creating antibacterial medication. The paper highlights the significance of dithiazolidines in medicinal chemistry in order to encourage research and further investigation of its applications and functions in medicine.